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What is Cialis?
Cialis (tadalafil) relaxes muscles and increases blood flow to particular areas of the body.
Cialis is used to treat erectile dysfunction (impotence) and symptoms of benign prostatic hypertrophy (enlarged prostate). Another brand of tadalafil is Adcirca, which is used to treat pulmonary arterial hypertension and improve exercise capacity in men and women.
Cialis may also be used for purposes not listed in this medication guide.
Important information
You should not use Cialis if you are allergic to tadalafil.
Do not take Cialis if you are also using a nitrate drug for chest pain or heart problems. This includes nitroglycerin, isosorbide dinitrate, and isosorbide mononitrate. Nitrates are also found in some recreational drugs such as amyl nitrate or nitrite ("poppers"). Taking Cialis with a nitrate medicine can cause a sudden and serious decrease in blood pressure.
Slideshow: Setting The Record Straight: Erectile Dysfunction
Setting The Record Straight: Erectile Dysfunction
Contact your doctor or seek emergency medical attention if your erection is painful or lasts longer than 4 hours. A prolonged erection (priapism) can damage the penis.
Stop using this medicine and get emergency medical help if you have sudden vision loss.
Before taking this medicine
You should not take Cialis if you are allergic to tadalafil.
Do not take Cialis if you are also using a nitrate drug for chest pain or heart problems. This includes nitroglycerin, isosorbide dinitrate, and isosorbide mononitrate. Nitrates are also found in some recreational drugs such as amyl nitrate or nitrite ("poppers"). Taking Cialis with a nitrate medicine can cause a sudden and serious decrease in blood pressure.
To make sure Cialis is safe for you, tell your doctor if you have any of these other conditions:
heart disease or heart rhythm problems, coronary artery disease;
a recent heart attack (within the past 90 days);
a recent history (in the past 6 months) of a stroke, or congestive heart failure;
angina (chest pain), high or low blood pressure;
liver or kidney disease (or if you are on dialysis);
a blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia;
a bleeding disorder such as hemophilia;
a stomach ulcer;
retinitis pigmentosa (an inherited condition of the eye);
a physical deformity of the penis (such as Peyronie's disease); or
if you have been told you should not have sexual intercourse for health reasons.
Cialis can decrease blood flow to the optic nerve of the eye, causing sudden vision loss. This has occurred in a small number of people taking Cialis, most of whom also had heart disease, diabetes, high blood pressure, high cholesterol, or certain pre-existing eye problems, and in those who smoke or are over 50 years old. Stop using Cialis and get emergency medical help if you have sudden vision loss.
FDA pregnancy category B. Cialis is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment with Adcirca.
See also: Pregnancy and breastfeeding warnings (in more detail)
It is not known whether tadalafil passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
How should I take Cialis?
Cialis is usually taken only once per day. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Cialis can be taken with or without food.
For erectile dysfunction, take the dose just before sexual activity but not more than once per day.
Cialis can help achieve an erection when sexual stimulation occurs. An erection will not occur just by taking a pill. Follow your doctor's instructions.
During sexual activity, if you become dizzy or nauseated, or have pain, numbness, or tingling in your chest, arms, neck, or jaw, stop and call your doctor right away. You could be having a serious side effect.
Do not break or split a tablet. Swallow it whole.
Do not take Cialis for erectile dysfunction if you are taking Adcirca for pulmonary arterial hypertension.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
If Cialis is used as needed, you are not likely to be on a dosing schedule.
If you take Cialis every day and you miss a dose, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid?
Grapefruit and grapefruit juice may interact with Cialis and lead to unwanted side effects. Avoid the use of grapefruit products while taking this medicine.
Drinking alcohol can increase certain side effects of Cialis.
Avoid using any other medicines to treat impotence, such as alprostadil or yohimbine, without first talking to your doctor.
Cialis side effects
Get emergency medical help if you have any of these signs of an allergic reaction to Cialis: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Contact your doctor or seek emergency medical attention if your erection is painful or lasts longer than 4 hours. A prolonged erection (priapism) can damage the penis.
Stop using Cialis and call your doctor at once if you have:
vision changes or sudden vision loss;
ringing in your ears, or sudden hearing loss;
chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
irregular heartbeat;
swelling in your hands, ankles, or feet;
shortness of breath;
seizure (convulsions); or
a light-headed feeling, like you might pass out.
Common Cialis side effects may include:
headache;
redness or warmth in your face, neck, or chest;
cold symptoms such as stuffy nose, sinus pain, sore throat, cough;
upset stomach; or
muscle pain, back pain, pain in your arms or legs.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
Cialis dosing information
Usual Adult Dose for Erectile Dysfunction:
Erectile dysfunction:
10 mg orally taken prior to anticipated sexual activity. The maximum recommended dosing frequency is once per day in most patients.
Alternatively, 2.5 mg orally once daily, without regard to timing of sexual activity. May increase to 5 mg orally once daily based on efficacy and tolerability.
Erectile dysfunction and benign prostatic hyperplasia together:
5 mg orally taken at approximately the same time every day.
Usual Adult Dose for Benign Prostatic Hyperplasia:
Benign prostatic hyperplasia and benign prostatic hyperplasia with erectile dysfunction:
5 mg orally taken at approximately the same time every day.
What other drugs will affect Cialis?
Tell your doctor about all medicines you use, and those you start or stop using during your treatment with Cialis, especially:
bosentan;
imatinib;
nefazodone;
St. John's wort;
an antibiotic--clarithromycin, erythromycin, telithromycin;
antifungal medication--itraconazole, ketoconazole, posaconazole, voriconazole;
heart or blood pressure medication--amlodipine nicardipine, quinidine;
hepatitis C medications--boceprevir, telaprevir;
HIV/AIDS medication--atazanavir, delavirdine, efavirenz, fosamprenavir, indinavir, nelfinavir, nevirapine, ritonavir, saquinavir;
seizure medication--carbamazepine, fosphenytoin, oxcarbazepine, phenobarbital, phenytoin, primidone; or
tuberculosis medication--isoniazid, rifabutin, rifampin, rifapentine.
This list is not complete. Other drugs may interact with tadalafil, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
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